Vaccination of advanced prostate cancer patients with PSCA and PSA peptide-loaded dendritic cells induces DTH responses that correlate with superior overall survival

Vaccination of advanced prostate cancer patients with PSCA and PSA peptide-loaded dendritic cells induces DTH responses that correlate with superior overall survival Contact Us Summary This trial was performed to demonstrate feasibility, safety and induction of antigen-specific immunity by vaccination with dendritic cells (DC) presenting PSCA and PSA peptides in patients with prostate cancer. Vaccination […]

Adoptive Immunotherapy for Pancreatic Cancer Using MUC1 Peptide-pulsed Dendritic Cells and Activated T Lymphocytes

Adoptive Immunotherapy for Pancreatic Cancer Using MUC1 Peptide-pulsed Dendritic Cells and Activated T Lymphocytes Contact Us Summary This study aims to determine the clinical efficacy of immunotherapy using both dendritic cells pulsed with MUC1 peptide (MUC1-DC) and, cytotoxic T lymphocyte (CTL) sensitized with a pancreatic cancer. The results suggest that adoptive immunotherapy with MUC1-DC and […]

Adoptive Immunotherapy for Pancreatic Cancer Using MUC1 Peptide-pulsed Dendritic Cells and Activated T Lymphocytes

Adoptive Immunotherapy for Pancreatic Cancer Using MUC1 Peptide-pulsed Dendritic Cells and Activated T Lymphocytes Contact Us Summary This trial investigated the efficacy and safety of this DC-based adjuvant immunotherapy with patients with Hepatocellular cancer. The results show that adjuvant immunotherapy with DC vaccine reduces the risk of tumour recurrence in HCC patients who underwent standard […]

Postoperative Adjuvant Dendritic Cell Based Immunotherapy in Patients with Relapsed Glioblastoma Multiforme

Postoperative Adjuvant Dendritic Cell Based Immunotherapy in Patients with Relapsed Glioblastoma Multiforme Contact Us Summary The aim of this study is to investigate the therapeutic role of adjuvant vaccination with autologous mature dendritic cells (DC) loaded with tumour lysates derived from autologous, resected glioblastoma multiforme (GBM) at time of relapse. The results suggest that the […]

Combination of External Beam Radiation (EBRT) with Intratumoral Injection of Dendritic Cells as Neo-Adjuvant Treatment of High-Risk Soft Tissue Sarcoma Patients

Combination of External Beam Radiation (EBRT) with Intratumoral Injection of Dendritic Cells as Neo-Adjuvant Treatment of High-Risk Soft Tissue Sarcoma Patients Contact Us Summary The aim of this study was to discover the effect of combination of dendritic cells (DC) and fractionated external beam radiation (EBRT) in patients with soft tissue sarcoma (STS). The results […]

A phase I/IIa study of adjuvant immunotherapy with tumour antigen-pulsed dendritic cells in patients with hepatocellular carcinoma

A phase I/IIa study of adjuvant immunotherapy with tumour antigen-pulsed dendritic cells in patients with hepatocellular carcinoma Contact Us Summary This study evaluated the safety and efficacy of adjuvant dendritic cell (DC) therapy in HCC patients who received primary treatment for hepatocellular carcinoma (HCC). Adjuvant DC vaccine for HCC was safe and well tolerated in […]