First results on survival from a large Phase 3 clinical trial of an autologous dendritic cell vaccine in newly diagnosed glioblastoma

First results on survival from a large Phase 3 clinical trial of an autologous dendritic cell vaccine in newly diagnosed glioblastoma MGMT Methylated Contact Us Summary This trial aims to evaluate the addition of an autologous tumor lysate-pulsed Dendritic Cell vaccine (DCVax®-L) to standard therapy for patients diagnosed with glioblastoma. The findings suggest the addition […]

Favorable overall survival in stage III melanoma patients after adjuvant dendritic cell vaccination

Favorable overall survival in stage III melanoma patients after adjuvant dendritic cell vaccination Overall survival rate Contact Us Summary The objective is analyze the safety and survival of melanoma patients with regional metastatic disease who underwent a RLND and received adjuvant DC vaccination. Introduction The incidence of cutaneous melanoma continues to rise worldwide. Adequate surgical […]

Dendritic Cell Vaccination Enhances Immune Responses and Induces Regression of HER2pos DCIS Independent of Route: Results of Randomized Selection Design Trial

Dendritic Cell Vaccination Enhances Immune Responses and Induces Regression of HER2pos DCIS Independent of Route: Results of Randomized Selection Design Trial SLN cumulative response Contact Us Summary This trial confirms the safety of neoadjuvant DC1 vaccination for patients with early invasive breast cancer (IBC). The immune response in the sentinel lymph nodes, may serve as […]

Selections of appropriate regimen of high-dose chemotherapy combined with adoptive cellular therapy with dendritic and cytokine-induced killer cells improved progression-free and overall survival in patients with metastatic breast cancer

Selections of appropriate regimen of high-dose chemotherapy combined with adoptive cellular therapy with dendritic and cytokine-induced killer cells improved progression-free and overall survival in patients with metastatic breast cancer Contact Us Summary In this study it was hypothesized that combination of dendritic cell (DC) with autologous cytokine-induced killer (CIK) immunotherapy in setting of high-dose chemotherapy […]

A novel potential effective strategy for enhancing the antitumor immune response in breast cancer patients using a viable cancer cell-dendritic cell-based vaccine

A novel potential effective strategy for enhancing the antitumor immune response in breast cancer patients using a viable cancer cell-dendritic cell-based vaccine Contact Us Summary Dendritic cells (DCs) have been used in a number of clinical trials for cancer immunotherapy, but, the success in treating solid tumors wiht DC is still limited. Therefore, the scope […]

Dendritic Cell Vaccine trial for Malignant Astrocytoma: potential interaction with adjuvant Chemotherapy

Dendritic Cell Vaccine trial for Malignant Astrocytoma: potential interaction with adjuvant Chemotherapy Clinical study on Malignant Astrocytoma Contact Us Summary Dendritic cell vaccination has been applied to the treatment of a variety of cancers, including malignant astrocytoma. In this study, 13 patients with malignant astrocytoma using dendritic cell vaccination were treated and have shown that […]