Immune response generated with the administration of autologous Dendritic Cells pulsed with an allogenic Tumoral Cell- lines lysate in patients with newly diagnosed diffuse intrinsic pontine glioma

Immune response generated with the administration of autologous Dendritic Cells pulsed with an allogenic Tumoral Cell- lines lysate in patients with newly diagnosed diffuse intrinsic pontine glioma Contact Us Summary This trial demonstrates the use of autologous dendritic cells (ADCs) pulsed with an allogeneic tumors cell-lines lysate in patients with newly diagnosed diffuse intrinsic pontine […]

Vaccination of Diffuse Large B- Cell Lymphoma Patients with Antigen-Primed Dendritic Cells

Vaccination of Diffuse Large B- Cell Lymphoma Patients with Antigen-Primed Dendritic Cells Contact Us Summary This study investigates the generation of monocyte-derived dendritic cells of lymphoma patient’s peripheral blood mononuclear cells then; these cells were used as vaccine. The results conclude that the use of dendritic cell probably is one of the suitable noninvasive treatments […]

Phase 1/2 Study of Immunotherapy With Dendritic Cells Pulsed With Autologous Tumor Lysate in Patients With Refractory Bone and Soft Tissue Sarcoma

Phase 1/2 Study of Immunotherapy With Dendritic Cells Pulsed With Autologous Tumor Lysate in Patients With Refractory Bone and Soft Tissue Sarcoma Contact Us Summary The purpose of this study was to assess the immunological and clinical effects of dendritic cells (DCs) pulsed with autologous tumor lysate (TL) in patients with advanced bone and soft […]

A gynecologic oncology group phase II trial of two p53 peptide vaccine approaches: subcutaneous injection and intravenous pulsed dendritic cells in high recurrence risk ovarian cancer patients

A gynecologic oncology group phase II trial of two p53 peptide vaccine approaches: subcutaneous injection and intravenous pulsed dendritic cells in high recurrence risk ovarian cancer patients Contact Us Summary This study describes the immune response elicited by two vaccine approaches using the wild-type (wt) p53 vaccine. The founding suggest that using either vaccination approach […]

Personalized neoantigen pulsed dendritic cell vaccine for advanced lung cancer

Personalized neoantigen pulsed dendritic cell vaccine for advanced lung cancer Contact Us Summary In this study, patients with lung cancer are treated with a personalised neoantigen peptide-pulsed autologous DC vaccine which reveals new therapeutic opportunities for lung cancer treatment. Patients characteristics Patients with histologically or cytologically confirmed lung cancer, including squamous cell carcinoma, adenocarcinoma, neuroendocrine […]

Surgery and adjuvant dendritic cell-based tumour vaccination for patients with relapsed malignant glioma, a feasibility study

Surgery and adjuvant dendritic cell-based tumour vaccination for patients with relapsed malignant glioma, a feasibility study Contact Us Summary DC loaded with proteins derived from autologous tumour homogenate is used for the treatment of patients with relapsed malignant glioma. As a result the approach may prolong survival of patients with malignant brain tumours without compromising […]