Phase 1/2 Study of Immunotherapy With Dendritic Cells Pulsed With Autologous Tumor Lysate in Patients With Refractory Bone and Soft Tissue Sarcoma
Phase 1/2 Study of Immunotherapy With Dendritic Cells Pulsed With Autologous Tumor Lysate in Patients With Refractory Bone and Soft Tissue Sarcoma Contact Us Summary The purpose of this study was to assess the immunological and clinical effects of dendritic cells (DCs) pulsed with autologous tumor lysate (TL) in patients with advanced bone and soft […]
A gynecologic oncology group phase II trial of two p53 peptide vaccine approaches: subcutaneous injection and intravenous pulsed dendritic cells in high recurrence risk ovarian cancer patients
A gynecologic oncology group phase II trial of two p53 peptide vaccine approaches: subcutaneous injection and intravenous pulsed dendritic cells in high recurrence risk ovarian cancer patients Contact Us Summary This study describes the immune response elicited by two vaccine approaches using the wild-type (wt) p53 vaccine. The founding suggest that using either vaccination approach […]
Neoantigen-Impfstoff gegen Lungenkrebs
Neoantigen-Impfstoff gegen Lungenkrebs Kontakt Überblick In dieser Studie werden Patienten mit Lungenkrebs mit einem personalisierten Neoantigen-Peptid-gepulsten autologen DC-Impfstoff behandelt, der neue therapeutische Möglichkeiten für die Behandlung von Lungenkrebs aufzeigt. Patientenmerkmale Patienten mit histologisch oder zytologisch bestätigtem Lungenkrebs, einschließlich Plattenepithelkarzinom, Adenokarzinom, neuroendokrinem Tumor und SCLC, im Alter zwischen 18 und 75 Jahren mit mindestens einer messbaren […]
Surgery and adjuvant dendritic cell-based tumour vaccination for patients with relapsed malignant glioma, a feasibility study
Surgery and adjuvant dendritic cell-based tumour vaccination for patients with relapsed malignant glioma, a feasibility study Contact Us Summary DC loaded with proteins derived from autologous tumour homogenate is used for the treatment of patients with relapsed malignant glioma. As a result the approach may prolong survival of patients with malignant brain tumours without compromising […]
Adjuvant Dendritic Cell-Based Tumour Vaccination for Children With Malignant Brain Tumours
Adjuvant Dendritic Cell-Based Tumour Vaccination for Children With Malignant Brain Tumours Contact Us Summary The study focuses on the results obtained in children with relapsed malignant brain tumours. the results primarily are promising and support further testing of DC-based immunotherapy in new treatment protocols for high grade glioma and Atypical Teratoid Rhabdoid Tumor. Patients characteristics […]
A phase II study of allogeneic natural killer cell therapy to treat patients with recurrent ovarian and breast cancer
A phase II study of allogeneic natural killer cell therapy to treat patients with recurrent ovarian and breast cancer Contact Us Summary In recurrent ovarian and breast cancer, researchers looked at the tumor response and in vivo proliferation of allogeneic NK cells.After lymphodepleting chemotherapy, adoptive transfer of haplo-identical NK cells causes transitory donor chimerism, which […]
