Category: Sarcomas

Before & After Treatment

Combination of External Beam Radiation (EBRT) with Intratumoral Injection of Dendritic Cells as Neo-Adjuvant Treatment of High-Risk Soft Tissue Sarcoma Patients

Combination of External Beam Radiation (EBRT) with Intratumoral Injection of Dendritic Cells as Neo-Adjuvant Treatment of High-Risk Soft Tissue Sarcoma Patients Contact Us Summary The aim of this study was to discover the effect of combination of dendritic cells (DC) and fractionated external beam radiation (EBRT) in patients with soft tissue sarcoma (STS). The results […]

Before and After Immunotherapy

Phase 1/2 Study of Immunotherapy With Dendritic Cells Pulsed With Autologous Tumor Lysate in Patients With Refractory Bone and Soft Tissue Sarcoma

Phase 1/2 Study of Immunotherapy With Dendritic Cells Pulsed With Autologous Tumor Lysate in Patients With Refractory Bone and Soft Tissue Sarcoma Contact Us Summary The purpose of this study was to assess the immunological and clinical effects of dendritic cells (DCs) pulsed with autologous tumor lysate (TL) in patients with advanced bone and soft […]

Presentation

Adjuvant Immunotherapy to Improve Outcome in High-Risk Pediatric Sarcomas

Adjuvant Immunotherapy to Improve Outcome in High-Risk Pediatric Sarcomas Contact Us Summary Patients with metastatic or relapsed pediatric sarcomas receive cytotoxic regimens that induce high remission rates associated with profound lymphocyte depletion, but ultimately few survive long term. We administered adjuvant immunotherapy to patients with metastatic and recurrent pediatric sarcomas in an effort to improve […]

Overall Survival

Cytokines Produced by Dendritic Cells Administered Intratumorally Correlate with Clinical Outcome in Patients with Diverse Cancers

Cytokines Produced by Dendritic Cells Administered Intratumorally Correlate with Clinical Outcome in Patients with Diverse Cancers Contact Us Summary This study investigates the correlation of cytokines produced by Dendritic Cells with clinical outcomes in patients with diverse cancers. The results reveal, aDC injections were feasible and safe. Increased production of specific cytokines was correlated with […]